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Health governance to fight the Covid-19 crisis and prevent future pandemics

Sentinel: A Pandemic Preemption System

  • African Centre of Excellence for Genomics of Infectious Diseases
  • Africa
  • 2021
  • Scale-up project

Project and organization presentation

Sentinel is a pandemic and outbreak early warning and response system that detects viral threats in real-time and prepares the global community to stop outbreaks before they spread. Jointly led by ACEGID (West Africa) and the Broad Institute (USA), Sentinel builds health system resilience in West Africa by detecting high-priority viruses, connecting public health stakeholders at all levels to real-time information, and empowering them to act on the data. The project has developed and currently validates a multiplex diagnostic system for rapidly detecting a wide array of viruses. When approved by regulatory authorities, the tool will be deployed as point-of-care testing. Sentinel has addressed the Covid-19 pandemic by establishing robust diagnostic and sequencing capacity in Nigeria and many African countries to support their responses.

 

 

Project trajectory over the past year

Through the Sentinel which is currently in its second year of implementation, ACEGID and the Broad Institute has refocused the project’s detect pillar and developed multiplexed diagnostic assay for high priority viruses in Africa. In the past year, Sentinel has also built the capacity of over 160 front-line health workers from 38 African countries on Next Generation Sequencing of SARS-CoV-2 and other emerging pathogens.

 

Impact

Through hands-on training, we have strengthened the capacity of 38 African countries to conduct genomic surveillance of SARS-CoV-2 and other pathogens using Next Generation Sequencing.

 

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